Unifiram
CAS No. 272786-64-8
Unifiram ( —— )
Catalog No. M28161 CAS No. 272786-64-8
Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 48 | In Stock |
|
5MG | 68 | In Stock |
|
10MG | 97 | In Stock |
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25MG | 174 | In Stock |
|
50MG | 280 | In Stock |
|
100MG | 442 | In Stock |
|
500MG | 990 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameUnifiram
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NoteResearch use only, not for human use.
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Brief DescriptionUnifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.
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DescriptionUnifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.(In Vivo):Unifiram (0.1 mg kg?1 i.p.) was able to prevent amnesia induced by scopolamine (0.8 mg kg?1 i.p.) in the rat Morris watermaze test. In the rat social learning test, Unifiram (0.1 mg kg?1 i.p.) injected in adults rats reduced the duration of active exploration of the familiar partner in the second session of the test. Unifiram, similarly to piracetam, reduced the duration of hypnosis induced by pentobarbital. At the highest effective doses, the investigated compound did not impair motor coordination (rota rod test), nor modified spontaneous (Animex).
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor15-PGDH
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Research Area——
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Indication——
Chemical Information
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CAS Number272786-64-8
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Formula Weight298.3
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Molecular FormulaC13H15FN2O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESFc1ccc(cc1)S(=O)(=O)N1CCN2C(CCC2=O)C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Niesen FH, et al. High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships. PLoS One. 2010 Nov 2;5(11):e13719.
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