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Ulinastatin

CAS No. 80449-31-6

Ulinastatin( Bikunin | Mingin | Miraclid | Trypsin inhibitor UTI | Urinary trypsin inhibitor 1 | Urinastatin )

Catalog No. M24803 CAS No. 80449-31-6

Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 61 In Stock
25MG 129 In Stock
50MG 205 In Stock
100MG 335 In Stock
200MG 494 In Stock
500MG 782 In Stock
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Biological Information

  • Product Name
    Ulinastatin
  • Note
    Research use only, not for human use.
  • Brief Description
    Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.
  • Description
    Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.
  • In Vitro
    Western Blot Analysis Cell Line:Human lung epithelial BEAS-2B cells Concentration:500 U, 2500 U, 5000 U Incubation Time:24 hours Result:Markedly attenuated TLR4 expression and NF-κB activation in LPS-stimulated BEAS-2B cells.
  • In Vivo
    Animal Model:Male C57BL/6 mice (8-10 weeks old, 18-22 g)Dosage:10000 U/kg Administration:i.v.; twice (1 h before and 6 h after LPS treatment)Result:Significantly protected animals from LPS-induced ALI.
  • Synonyms
    Bikunin | Mingin | Miraclid | Trypsin inhibitor UTI | Urinary trypsin inhibitor 1 | Urinastatin
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Kunitz-type serine protease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    80449-31-6
  • Formula Weight
    ——
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 10 mg/mL
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nakahama H , Kuribayashi K , Sugita M , et al. Cytoprotective effect of ulinastatin, a Kunitz-type protease inhibitor, on hypoxic injury in L2 cells treated with antimycin A via stabilization of lysosomal fragility.[J]. Pulmonary Pharmacology & Therapeutics, 1999, 12(1):1-6.
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