USP10-IN-3

CAS No. 904448-58-4

USP10-IN-3 ( —— )

Catalog No. M16503 CAS No. 904448-58-4

USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    USP10-IN-3
  • Note
    Research use only, not for human use.
  • Brief Description
    USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM).
  • Description
    USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM); demonstrates specificity for FLT3- mutant MOLM13-luc+, MOLM14 and MV4,11 cell lines relative to the FLT3-null TF-1 cell line and to other leukemia lines not driven by FLT3.
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    DUB
  • Recptor
    DUB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    904448-58-4
  • Formula Weight
    401.98
  • Molecular Formula
    C23H32ClN3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCCN(CCC)CCCNC(=O)C1=CC2=C(C=C1)C(=C3CCCCC3=N2)Cl
  • Chemical Name
    9-chloro-N-(3-(dipropylamino)propyl)-5,6,7,8-tetrahydroacridine-3-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Weisberg EL, et al. Nat Chem Biol. 2017 Dec;13(12):1207-1215.
molnova catalog
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