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UNC6934

CAS No. 2561494-77-5

UNC6934( —— )

Catalog No. M28780 CAS No. 2561494-77-5

UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

UNC6934
Note

Research use only, not for human use.
Brief Description

UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.
Description

UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.(In Vitro):UNC6934 occupies the canonical H3K36me2-binding pocket of PWWP1, antagonizes PWWP1 interaction with nucleosomal H3K36me2 and selectively engages endogenous NSD2 in cells.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

ATPase|Potassium Channel|Sodium Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

2561494-77-5
Formula Weight

443.45
Molecular Formula

C24H21N5O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 25 mg/mL (56.38 mM)
SMILES

O=C(c1ccc(CN(C2CC2)C(c(cc2)cc(OC3)c2NC3=O)=O)cc1)Nc1ncncc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Kohls S, et al. Method validation of a survey of thevetia cardiac glycosides in serum samples. Forensic Sci Int. 2012 Feb 10;215(1-3):146-51.

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