Cart
sales@molnova.com
UNC0631
CAS No. 1320288-19-4
UNC0631 ( UNC0631, UNC 0631, UNC-0631 )
Catalog No. M17245 CAS No. 1320288-19-4
UNC0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 61 | In Stock |
|
| 5MG | 101 | In Stock |
|
| 10MG | 177 | In Stock |
|
| 25MG | 378 | In Stock |
|
| 50MG | 556 | In Stock |
|
| 100MG | 777 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameUNC0631
-
NoteResearch use only, not for human use.
-
Brief DescriptionUNC0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).
-
DescriptionUNC-0631 is a novel G9a inhibitor with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity. Protein lysine methyltransferase G9a plays key roles in the transcriptional repression of a variety of genes via dimethylation of lysine 9 on histone H3 (H3K9me2) of chromatin as well as dimethylation of nonhistone proteins including tumor suppressor p53.
-
SynonymsUNC0631, UNC 0631, UNC-0631
-
PathwayAngiogenesis
-
TargetEGFR
-
RecptorG9a
-
Research AreaOthers-Field
-
Indication——
Chemical Information
-
CAS Number1320288-19-4
-
Formula Weight635.93
-
Molecular FormulaC37H61N7O2
-
Purity98%
-
SolubilityDMSO : 16.67 mg/mL. 26.21 mM; H2O : < 0.1 mg/mL
-
SMILESCOc1c(OCCCN2CCCCC2)cc2nc(nc(NC3CCN(CC4CCCCC4)CC3)c2c1)N1CCCN(CC1)C(C)C
-
Chemical NameN-(1-(cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Liu F, et al. J Med Chem. 2011, 54(17), 6139-6150.
molnova catalog
related products
-
PD 174265
PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.
-
Tyrphostin B44, (+) ...
Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.
-
7,8-Dihydroxyflavone
7, 8-Dihydroxyflavone (7, 8-DHF) is a naturally-occurring flavone and exist in Tridax procumbens, Godmania aesculifolia, and primula tree leaves.
