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Home - Products - Cell Cycle/DNA Damage - DNA/RNA Synthesis - UM-164

UM-164

CAS No. 903564-48-7

UM-164 ( UM-164; UM 164; UM164 )

Catalog No. M19247 CAS No. 903564-48-7

UM-164 is a highly potent inhibitor ofc-Srcwith aKdof 2.7 nM. UM-164 also potently inhibitsp38αandp38β.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 39 In Stock
5MG 61 In Stock
10MG 110 In Stock
25MG 178 In Stock
50MG 267 In Stock
100MG 395 In Stock
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Biological Information

  • Product Name
    UM-164
  • Note
    Research use only, not for human use.
  • Brief Description
    UM-164 is a highly potent inhibitor ofc-Srcwith aKdof 2.7 nM. UM-164 also potently inhibitsp38αandp38β.
  • Description
    UM-164 is a Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer.
  • Synonyms
    UM-164; UM 164; UM164
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    c-Src;p38α;p38β
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    903564-48-7
  • Formula Weight
    640.68
  • Molecular Formula
    C30H31F3N8O3S
  • Purity
    98%
  • Solubility
    DMSO : 5 mg/mL 7.80 mM;H2O : < 0.1 mg/mL
  • SMILES
    FC(F)(F)c1cccc(c1)C(=O)Nc5cc(NC(=O)c4cnc(Nc2nc(C)nc(c2)N3CCN(CCO)CC3)s4)c(C)cc5
  • Chemical Name
    2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]-5-thiazolecarboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gilani RA, et al. UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer. Clin Cancer Res. 2016 Oct 15;22(20):5087-5096.
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