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UM-164
CAS No. 903564-48-7
UM-164 ( UM-164; UM 164; UM164 )
Catalog No. M19247 CAS No. 903564-48-7
UM-164 is a highly potent inhibitor ofc-Srcwith aKdof 2.7 nM. UM-164 also potently inhibitsp38αandp38β.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 39 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 110 | In Stock |
|
| 25MG | 178 | In Stock |
|
| 50MG | 267 | In Stock |
|
| 100MG | 395 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUM-164
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NoteResearch use only, not for human use.
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Brief DescriptionUM-164 is a highly potent inhibitor ofc-Srcwith aKdof 2.7 nM. UM-164 also potently inhibitsp38αandp38β.
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DescriptionUM-164 is a Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer.
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SynonymsUM-164; UM 164; UM164
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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Recptorc-Src;p38α;p38β
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Research Area——
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Indication——
Chemical Information
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CAS Number903564-48-7
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Formula Weight640.68
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Molecular FormulaC30H31F3N8O3S
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Purity98%
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SolubilityDMSO : 5 mg/mL 7.80 mM;H2O : < 0.1 mg/mL
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SMILESFC(F)(F)c1cccc(c1)C(=O)Nc5cc(NC(=O)c4cnc(Nc2nc(C)nc(c2)N3CCN(CCO)CC3)s4)c(C)cc5
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Chemical Name2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]-5-thiazolecarboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Gilani RA, et al. UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer. Clin Cancer Res. 2016 Oct 15;22(20):5087-5096.
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