ULK-101( —— )

Catalog No. M24125 CAS No. 2443816-45-1

ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	218	In Stock
5MG	335	In Stock
10MG	537	In Stock
25MG	842	In Stock
50MG	1134	In Stock
100MG	1521	In Stock
500MG	3042	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ULK-101
Note

Research use only, not for human use.
Brief Description

ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
Description

ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
In Vitro

ULK-101 (0-5 μM) reduces BafA1-induced LC3B-II accumulation in U2OS cells in a concentration-dependent manner.
In Vivo

——
Synonyms

——
Pathway

Autophagy
Target

Autophagy
Recptor

ULK1
Research Area

——
Indication

——

Chemical Information

CAS Number

2443816-45-1
Formula Weight

460.4
Molecular Formula

C22H16F4N4OS
Purity

>98% (HPLC)
Solubility

DMSO:84mg/mL (182.43mM)
SMILES

O=C(C1=CC(C2=C3N=CC(C4=CC=C(F)C=C4)=CN3N=C2)=CS1)N[C@@H](C5CC5)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Martin KR, Celano SL, Solitro AR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018;8:74-84. doi:10.1016/j.isci.2018.09.012

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