
UK-396082
CAS No. 400044-47-5
UK-396082( UK 396,082 | UK396082 )
Catalog No. M14370 CAS No. 400044-47-5
UK-396082 is a potent and selective inhibitor of activated thrombin-activatable fibrinolysis inhibitor (activated TAFI; TAFIa) with Ki of 10 nM.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 963 | Get Quote |
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50MG | 1962 | Get Quote |
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100MG | 2520 | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameUK-396082
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NoteResearch use only, not for human use.
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Brief DescriptionUK-396082 is a potent and selective inhibitor of activated thrombin-activatable fibrinolysis inhibitor (activated TAFI; TAFIa) with Ki of 10 nM.
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DescriptionUK-396082 is a potent and selective inhibitor of activated thrombin-activatable fibrinolysis inhibitor (activated TAFI; TAFIa) with Ki of 10 nM; displays excellent selectivity over plasma carboxypeptidase N (>1,000-fold); exhibits antithrombotic efficacy in a rabbit model of venous thrombosis, yet has no effect on surgical bleeding in the rabbit; possesses excellent preclinical and clinical pharmacokinetic profile, and shows potential for the treatment of thrombosis and other fibrin-dependent diseases in humans.Thrombosis Phase 1 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsUK 396,082 | UK396082
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaCardiovascular Disease
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IndicationThrombosis
Chemical Information
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CAS Number400044-47-5
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Formula Weight239.319
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Molecular FormulaC12H21N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCN1C=C(N=C1)C[C@H](CCCN)C(=O)O
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Chemical Name(S)-5-amino-2-((1-propyl-1H-imidazol-4-yl)methyl)pentanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference



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