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Home - Products - Membrane Transporter/Ion Channel - GAT - U-93631

U-93631

CAS No. 152273-12-6

U-93631( U93631 | U 93631 )

Catalog No. M12126 CAS No. 152273-12-6

A potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 58 In Stock
25MG 115 In Stock
50MG 178 In Stock
100MG 332 In Stock
500MG 782 In Stock
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Biological Information

  • Product Name
    U-93631
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction.
  • Description
    A potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction; induce a rapid, time-dependent decay of GABA-induced whole-cell Cl- currents in recombinant GABAA receptors.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    U93631 | U 93631
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    GAT
  • Recptor
    GABA
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    152273-12-6
  • Formula Weight
    299.3676
  • Molecular Formula
    C17H21N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 34 mg/mL
  • SMILES
    O=C(C1=C2N(C=N1)C3=C(C=CC=C3)NC2(C)C)OC(C)(C)C
  • Chemical Name
    Imidazo[1,5-a]quinoxaline-3-carboxylic acid, 4,5-dihydro-4,4-dimethyl-, 1,1-dimethylethyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dillon GH, et al. Mol Pharmacol. 1993 Oct;44(4):860-5. 2. Dillon GH, et al. J Pharmacol Exp Ther. 1995 Feb;272(2):597-603. 3. Dillon GH, et al. Br J Pharmacol. 1995 Jun;115(3):539-45.
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