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Trofinetide
CAS No. 853400-76-7
Trofinetide( NNZ 2566 )
Catalog No. M16197 CAS No. 853400-76-7
Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 273 | Get Quote |
|
| 10MG | 413 | Get Quote |
|
| 25MG | 680 | Get Quote |
|
| 50MG | 954 | Get Quote |
|
| 100MG | 1287 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTrofinetide
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NoteResearch use only, not for human use.
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Brief DescriptionTrofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
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DescriptionTrofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration; improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury; significantly reduces injury-mediated up-regulation of IL-1beta, TNF-alpha, E-selectin and IL-6 mRNA in the injured brain in rats.Other Indication Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsNNZ 2566
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number853400-76-7
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Formula Weight315.322
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Molecular FormulaC13H21N3O6
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Purity>98% (HPLC)
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SolubilityH2O : ≥ 50 mg/mL 158.57 mM
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SMILESO=C(O)CC[C@@H](C(O)=O)NC([C@@]1(C)N(C(CN)=O)CCC1)=O
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Chemical Name((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bickerdike MJ, et al. J Neurol Sci. 2009 Mar 15;278(1-2):85-90.
2. Lu XC, et al. J Cereb Blood Flow Metab. 2009 Dec;29(12):1924-32.
3. Wei HH, et al. J Neuroinflammation. 2009 Aug 5;6:19.
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