Trofinetide

CAS No. 853400-76-7

Trofinetide ( NNZ 2566 )

Catalog No. M16197 CAS No. 853400-76-7

Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 273 Get Quote
10MG 413 Get Quote
25MG 680 Get Quote
50MG 954 Get Quote
100MG 1287 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Trofinetide
  • Note
    Research use only, not for human use.
  • Brief Description
    Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
  • Description
    Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration; improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury; significantly reduces injury-mediated up-regulation of IL-1beta, TNF-alpha, E-selectin and IL-6 mRNA in the injured brain in rats.Other Indication Phase 2 Clinical
  • Synonyms
    NNZ 2566
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    853400-76-7
  • Formula Weight
    315.32
  • Molecular Formula
    C13H21N3O6
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : ≥ 50 mg/mL 158.57 mM
  • SMILES
    O=C(O)CC[C@@H](C(O)=O)NC([C@@]1(C)N(C(CN)=O)CCC1)=O
  • Chemical Name
    ((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bickerdike MJ, et al. J Neurol Sci. 2009 Mar 15;278(1-2):85-90.
2. Lu XC, et al. J Cereb Blood Flow Metab. 2009 Dec;29(12):1924-32.
3. Wei HH, et al. J Neuroinflammation. 2009 Aug 5;6:19.
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