Transketolase-IN-4( —— )

Catalog No. M36468 CAS No. 419547-73-2

Transketolase-IN-4 is a transketolase inhibitor with an IC50 value of 3.9 μM.Transketolase-IN-4 inhibited Mycobacterium tuberculosis DXS with an IC50 value of 114.1 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Transketolase-IN-4
Note

Research use only, not for human use.
Brief Description

Transketolase-IN-4 is a transketolase inhibitor with an IC50 value of 3.9 μM.Transketolase-IN-4 inhibited Mycobacterium tuberculosis DXS with an IC50 value of 114.1 μM.
Description

Transketolase-IN-4 is a potent transketolase inhibitor (IC50=3.9 μM). Transketolase-IN-4 inhibits tumor cell proliferation of SW620, LS174T, and MIA PaCa-2. Transketolase-IN-4 is a possible Mycobacterium tuberculosis DXS inhibitor, with an IC50 value of 114.1 μM.
In Vitro

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In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Transketolase | Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

419547-73-2
Formula Weight

335.79
Molecular Formula

C19H14ClN3O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (372.26 mM; Ultrasonic )
SMILES

O=C1N2C(=C(C=N2)C3=CC=C(Cl)C=C3)NC(CC4=CC=CC=C4)=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Du MX, et al. Identification of novel small-molecule inhibitors for human transketolase by high-throughput screening with fluorescent intensity (FLINT) assay. J Biomol Screen. 2004 Aug;9(5):427-33.?

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