Transketolase-IN-4

CAS No. 419547-73-2

Transketolase-IN-4( —— )

Catalog No. M36468 CAS No. 419547-73-2

Transketolase-IN-4 is a transketolase inhibitor with an IC50 value of 3.9 μM.Transketolase-IN-4 inhibited Mycobacterium tuberculosis DXS with an IC50 value of 114.1 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 49 Get Quote
5MG 69 Get Quote
10MG 112 Get Quote
25MG 228 Get Quote
50MG 364 Get Quote
100MG 583 Get Quote
500MG 1215 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Transketolase-IN-4
  • Note
    Research use only, not for human use.
  • Brief Description
    Transketolase-IN-4 is a transketolase inhibitor with an IC50 value of 3.9 μM.Transketolase-IN-4 inhibited Mycobacterium tuberculosis DXS with an IC50 value of 114.1 μM.
  • Description
    Transketolase-IN-4 is a potent transketolase inhibitor (IC50=3.9 μM). Transketolase-IN-4 inhibits tumor cell proliferation of SW620, LS174T, and MIA PaCa-2. Transketolase-IN-4 is a possible Mycobacterium tuberculosis DXS inhibitor, with an IC50 value of 114.1 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Transketolase | Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    419547-73-2
  • Formula Weight
    335.79
  • Molecular Formula
    C19H14ClN3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (372.26 mM; Ultrasonic )
  • SMILES
    O=C1N2C(=C(C=N2)C3=CC=C(Cl)C=C3)NC(CC4=CC=CC=C4)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Du MX, et al. Identification of novel small-molecule inhibitors for human transketolase by high-throughput screening with fluorescent intensity (FLINT) assay. J Biomol Screen. 2004 Aug;9(5):427-33.?
molnova catalog
related products
  • Katacalcin

    Katacalcin (PDN 21) is a potent plasma calcium-lowering peptide.

  • SMS2-IN-2

    SMS2-IN-2 is a potent selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50s of 100 and 56 μM for SMS2 and SMS1 respectively). SMS2-IN-2 has anti-chronic inflammatory activity.

  • Nortriptyline

    Nortriptyline is an antidepressant compound that enhances corticosteroid sensitivity of blood T-cells in patients with chronic obstructive pulmonary disease (COPD) and may be used for smoking cessation.