Tomatine

Research use only, not for human use.

An antiproliferatve agent of breast adenocarcinoma cells.

Tomatine is a glycoalkaloid found in the tomato plant (Lycopersicon esculentum Mill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity.

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lycopersicin

Others

Other Targets

Others

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17406-45-0

1034.2

C50H83NO21

>98% (HPLC)

DMSO:96.7 mM

C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@H]5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O[C@@H]4OC[C@@H](O)[C@H](O)[C@H]4O)[C@H]3O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)O[C@@]11CC[C@H](C)CN1

(2S3R4S5S6R)-2-(((2S3R4S5R6R)-2-(((2R3R4R5R6R)-45-dihydroxy-2-(hydroxymethyl)-6-(((2aS4S5'S6aS6bS8aS8bR9S10S11aS12aS12bR)-5'6a8a9-tetramethyloctadecahydrospiro[naphtho[2'1':45]indeno[21-b]furan-102'-piperidin]-4-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-5-hydroxy-6-(hydroxymethyl)-4-(((2S3R4S5R)-345-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-345-triol

(-20℃)

With Ice Pack

≥ 2 years