Tofisopam

Research use only, not for human use.

Tofisopam is a 2,3-benzodiazepine derivative with anti-anxiety property.

Tofisopam is a 2,3-benzodiazepine derivative with anti-anxiety property.(In Vivo):Tofisopam (30 and 100 mg/kg, po) significantly inhibited the gastric ulceration induced by water-immersion stress in normal rats in a dose-dependent manner. Immobilization-stress loading increased the incidence and average index of gastric ulceration in OB rats, compared with nonstressed rats. Tofisopam (100 mg/kg, po) significantly inhibited the gastric ulceration induced by stress loading in OB rats. Water-immersion stress loading induced a significant increase in intestinal propulsion in rats. This increase was reversed to control levels by tofisopam (100 mg/kg, po). Tofisopam (1.0 mg/kg, iv, or 0.1 mg/kg by intracerebrospinal injection) inhibited the constriction of ear microvessels, the decrease in earlobe temperature, and mydriasis induced by electrical stimulation of the medial hypothalamic area in rabbits.

Emandaxin | Grandaxin

Others

Other Targets

HIV|clathrin

22345-47-7

382.46

C22H26N2O4

>98% (HPLC)

CCC1c2cc(OC)c(OC)cc2C(=NN=C1C)c1ccc(OC)c(OC)c1

(-20℃)

With Ice Pack

≥ 2 years