Cart
sales@molnova.com
Home - Products - Others - Other Targets - Tofisopam

Tofisopam

CAS No. 22345-47-7

Tofisopam ( Emandaxin; Grandaxin )

Catalog No. M28018 CAS No. 22345-47-7

Tofisopam is a 2,3-benzodiazepine derivative with anti-anxiety property.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 61 Get Quote
10MG 88 Get Quote
25MG 159 Get Quote
50MG 228 Get Quote
100MG 335 Get Quote
200MG 491 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Tofisopam
  • Note
    Research use only, not for human use.
  • Brief Description
    Tofisopam is a 2,3-benzodiazepine derivative with anti-anxiety property.
  • Description
    Tofisopam is a 2,3-benzodiazepine derivative with anti-anxiety property.(In Vivo):Tofisopam (30 and 100 mg/kg, po) significantly inhibited the gastric ulceration induced by water-immersion stress in normal rats in a dose-dependent manner. Immobilization-stress loading increased the incidence and average index of gastric ulceration in OB rats, compared with nonstressed rats. Tofisopam (100 mg/kg, po) significantly inhibited the gastric ulceration induced by stress loading in OB rats. Water-immersion stress loading induced a significant increase in intestinal propulsion in rats. This increase was reversed to control levels by tofisopam (100 mg/kg, po). Tofisopam (1.0 mg/kg, iv, or 0.1 mg/kg by intracerebrospinal injection) inhibited the constriction of ear microvessels, the decrease in earlobe temperature, and mydriasis induced by electrical stimulation of the medial hypothalamic area in rabbits.
  • Synonyms
    Emandaxin; Grandaxin
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    HIV;clathrin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    22345-47-7
  • Formula Weight
    382.5
  • Molecular Formula
    C22H26N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCC1c2cc(OC)c(OC)cc2C(=NN=C1C)c1ccc(OC)c(OC)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lisa von Kleist, et al. Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell. 2011 Aug 5;146(3):471-84.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Erythrosine

    A tetraiodofluorescein used as a red coloring in some foods (cherries, fish), as a disclosure of DENTAL PLAQUE, and as a stain of some cell types. It has structural similarity to THYROXINE.

  • Benzoylaconitine

    Benzoylaconine is an alkaloid in the Chinese traditional medicine Radix Aconiti Lateralis Preparata (Fuzi). Benzoylaconine and aconitine can induce reproductive toxicity in BeWo Cell the amino acid metabolism was the main metabolic pathway and responsible for the placental and fetal toxicity of them.

  • Eupatoriochromene

    Eupatoriochromene retard seed germination , reduced radicle and hypocotyl growth of weed and crop plant seedlings and increased adventitious root formation of mung bean cuttings. Eupatoriochromene has insecticidal activity, it exhibits toxicity againstCulex pipiens (house mosquito) larvae andOncopeltus fasciatus (large milkweed bug) nymphs.

Sign In Join Free