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Tirapazamine
CAS No. 27314-97-2
Tirapazamine ( Tirapazamine; Tirazone; SR 4233; SR-4233; WIN 59075 )
Catalog No. M18344 CAS No. 27314-97-2
Tirapazamine is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks.
Purity : 97%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 27 | In Stock |
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| 25MG | 40 | In Stock |
|
| 50MG | 55 | In Stock |
|
| 100MG | 92 | In Stock |
|
| 200MG | 146 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTirapazamine
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NoteResearch use only, not for human use.
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Brief DescriptionTirapazamine is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks.
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DescriptionTrapazamine, also known as SR-4233,DNA-damaging drug potentially for the treatment of cervical carcinoma, head and neck cancer. Tirapazamine is activated to its toxic form preferentially in the hypoxic areas of solid tumors. Cells in these regions are resistant to killing by radiotherapy and most anticancer drugs. Thus the combination of tirapazamine with conventional anticancer treatments is particularly effective.
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SynonymsTirapazamine; Tirazone; SR 4233; SR-4233; WIN 59075
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number27314-97-2
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Formula Weight178.15
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Molecular FormulaC7H6N4O2
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Purity97%
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SolubilityDMSO : ≥ 39 mg/m; 218.92 mM
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SMILESNc1nn(=O)c2ccccc2n1=O
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Chemical Name3-aminobenzo[e][1,2,4]triazine 1,4-dioxide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cai T Y, Liu X W, Zhu H, et al. Molecular cancer therapeutics, 2013: molcanther. 0490.2013.
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