Tirapazamine ( Tirapazamine; Tirazone; SR 4233; SR-4233; WIN 59075 )

Catalog No. M18344 CAS No. 27314-97-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

Tirapazamine
Note

Research use only, not for human use.
Brief Description

Tirapazamine is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks.
Description

Trapazamine, also known as SR-4233,DNA-damaging drug potentially for the treatment of cervical carcinoma, head and neck cancer. Tirapazamine is activated to its toxic form preferentially in the hypoxic areas of solid tumors. Cells in these regions are resistant to killing by radiotherapy and most anticancer drugs. Thus the combination of tirapazamine with conventional anticancer treatments is particularly effective.
Synonyms

Tirapazamine; Tirazone; SR 4233; SR-4233; WIN 59075
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Cancer
Indication

——

1.Cai T Y, Liu X W, Zhu H, et al. Molecular cancer therapeutics, 2013: molcanther. 0490.2013.

Calculator

molnova catalog