Tiazofurin( NSC 286193 | Riboxamide )

Catalog No. M28325 CAS No. 60084-10-8

Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) .

Purity : >98% (HPLC)

COA

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HNMR

HPLC

MSDS

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Biological Information

Product Name

Tiazofurin
Note

Research use only, not for human use.
Brief Description

Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) .
Description

Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) .
In Vitro

——
In Vivo

——
Synonyms

NSC 286193 | Riboxamide
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

Antifungal
Research Area

——
Indication

——

Chemical Information

CAS Number

60084-10-8
Formula Weight

260.26
Molecular Formula

C9H12N2O5S
Purity

>98% (HPLC)
Solubility

——
SMILES

NC(=O)c1csc(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Moraes DC, et al. β-lapachone and α-nor-lapachone modulate Candida albicans viability and virulence factors. J Mycol Med. 2018 Mar 26. pii: S1156-5233(17)30379-7.

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