Thioguanine
CAS No. 154-42-7
Thioguanine ( —— )
Catalog No. M18075 CAS No. 154-42-7
Thioguanine is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Purity : 98%
Size | Price / USD | Stock | Quantity |
50MG | 36 | In Stock |
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100MG | 43 | In Stock |
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500MG | 65 | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameThioguanine
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NoteResearch use only, not for human use.
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Brief DescriptionThioguanine is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
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DescriptionTioguanine (INN, BAN), or thioguanine (AAN, USAN), commonly referred to as 6-thioguanine (6-TG) is a medication used to treat a number of types of leukemia. It has been used less frequently in recent years because of safety concerns. However, it is becoming more widely used for treating ulcerative colitis and some autoimmune diseases.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorDNMT1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number154-42-7
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Formula Weight167.2
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Molecular FormulaC5H5N5S
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Purity98%
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SolubilityDMSO : 10 mg/mL 59.81 mM;
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SMILESc1nc2c([nH]1)c(=S)nc([nH]2)N
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Chemical Name2-amino-1H-purine-6(7H)-thione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Fz7-21 TFA (2247635-...
Fz7-21 TFA ((Ac)-LPSDDLEFWCHVMY-NH2 TFA), a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively.
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Chaetocin
Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively.
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Phenyl-ac-Gly-OH
Phenylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. The presence of phenylacetylglycine in urine has been confirmed for dogs rats and mice. However the presence of this compound in human urine is controversial. GC-MS studies have not found this compound while NMR studies claimed to have identified it.