Thalidomide-propargyl
CAS No. 2098487-39-7
Thalidomide-propargyl ( —— )
Catalog No. M27023 CAS No. 2098487-39-7
Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
2MG | 35 | Get Quote |
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5MG | 58 | Get Quote |
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10MG | 98 | Get Quote |
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25MG | 178 | Get Quote |
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50MG | 308 | Get Quote |
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100MG | 461 | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameThalidomide-propargyl
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NoteResearch use only, not for human use.
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Brief DescriptionThalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein.
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DescriptionThalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-propargyl can be connected to the ligand for protein by a linker to form the IMiD containing PROTACs.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorHuman Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number2098487-39-7
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Formula Weight312.3
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Molecular FormulaC16H12N2O5
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1N(C2CCC(=O)NC2=O)C(=O)c2c1cccc2OCC#C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Protein kinase inhib...
Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
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RH01386
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.