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Thalidomide-PEG4-Propargyl

CAS No. 2098799-77-8

Thalidomide-PEG4-Propargyl ( Thalidomide-O-PEG4-Propargyl )

Catalog No. M28653 CAS No. 2098799-77-8

Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Thalidomide-PEG4-Propargyl
  • Note
    Research use only, not for human use.
  • Brief Description
    Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology.
  • Description
    Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology.
  • Synonyms
    Thalidomide-O-PEG4-Propargyl
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    estrogen receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2098799-77-8
  • Formula Weight
    488.5
  • Molecular Formula
    C24H28N2O9
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C#CCOCCOCCOCCOCCOc1cccc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gauthier S1,et al.Synthesis and structure-activity relationships of analogs of EM-652 (acolbifene), a pure selective estrogen receptor modulator. Study of nitrogen substitution.J Enzyme Inhib Med Chem. 2005 Apr;20(2):165-77.
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