Thalidomide-NH-CH2-COOH

CAS No. 927670-97-1

Thalidomide-NH-CH2-COOH ( (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine; 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid )

Catalog No. M28260 CAS No. 927670-97-1

Thalidomide-NH-CH2-COOH is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 33 In Stock
10MG 46 In Stock
25MG 72 In Stock
50MG 104 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Thalidomide-NH-CH2-COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    Thalidomide-NH-CH2-COOH is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
  • Description
    Thalidomide-NH-CH2-COOH is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • Synonyms
    (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine; 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    α7 nAChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    927670-97-1
  • Formula Weight
    331.3
  • Molecular Formula
    C15H13N3O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(CNc1cccc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lagostena L, et al. The partial alpha7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus. Neuropharmacology. 2008 Mar;54(4):676-85.
molnova catalog
related products