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Thalidomide-NH-C4-NH-Boc
CAS No. 2093388-52-2
Thalidomide-NH-C4-NH-Boc ( —— )
Catalog No. M23941 CAS No. 2093388-52-2
Thalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 97 | In Stock |
|
| 10MG | 151 | In Stock |
|
| 25MG | 305 | In Stock |
|
| 50MG | 462 | In Stock |
|
| 100MG | 672 | In Stock |
|
| 500MG | 1404 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameThalidomide-NH-C4-NH-Boc
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NoteResearch use only, not for human use.
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Brief DescriptionThalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
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DescriptionThalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
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Synonyms——
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PathwayPROTACs
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TargetE3 Ligase Ligand
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RecptorCereblon
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Research Area——
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Indication——
Chemical Information
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CAS Number2093388-52-2
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Formula Weight444.5
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Molecular FormulaC22H28N4O6
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (112.49 mM; Need ultrasonic)
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SMILESCC(C)(C)OC(=O)NCCCCNC1=CC=CC2=C1C(=O)N(C2=O)C3CCC(=O)NC3=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jiang F, et al.Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies.Bioorg Med Chem. 2020 Jan 1;28(1):115181.
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