Thalidomide-5-methyl
CAS No. 40313-92-6
Thalidomide-5-methyl ( —— )
Catalog No. M28307 CAS No. 40313-92-6
Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 393 | Get Quote |
|
10MG | 581 | Get Quote |
|
25MG | 888 | Get Quote |
|
50MG | 1242 | Get Quote |
|
100MG | 1674 | Get Quote |
|
500MG | 3348 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameThalidomide-5-methyl
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NoteResearch use only, not for human use.
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Brief DescriptionThalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
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DescriptionThalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorhDHODH
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Research Area——
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Indication——
Chemical Information
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CAS Number40313-92-6
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Formula Weight272.3
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Molecular FormulaC14H12N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCc(cc1)cc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lewis TA, et al. Development?of?ML390: A?Human?DHODH?Inhibitor?That?Induces?Differentiation?in?Acute?Myeloid?Leukemia. ACS Med Chem Lett.?2016 Sep 28;7(12):1112-1117.
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