Terbufibrol

CAS No. 56488-59-6

Terbufibrol( —— )

Catalog No. M33239 CAS No. 56488-59-6

Terbufibrol reduces the levels of serum total cholesterol in normal and hypercholesterolemic male rats.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 260 Get Quote
5MG 319 Get Quote
10MG 540 Get Quote
25MG 840 Get Quote
50MG 1132 Get Quote
100MG 1512 Get Quote
500MG 3024 Get Quote
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Biological Information

  • Product Name
    Terbufibrol
  • Note
    Research use only, not for human use.
  • Brief Description
    Terbufibrol reduces the levels of serum total cholesterol in normal and hypercholesterolemic male rats.
  • Description
    Terbufibrol has been shown highly active in reducing serum total cholesterol (TC) levels in the normal and hypercholesterolemic male rat.
  • In Vitro
    ——
  • In Vivo
    Terbufibrol (20-200 mg/kg) is active in lowering serum TC in animals on all 3 diets, but the extent of cholesterol reduction varies in the order cholesterol (HC)>high protein and fat diet (HPF)>N (max. reductions: 154, 80, and 70%, respectively). Clofibrate (200 mg/kg) decreases TC by a maximum of 28% with the HPF-diet and 13% with the N-diet but is inactive with the HC-diet. Cholestyramine (400 mg/kg/day) is inactive in HPF-fed animals but reduces TC in HC-fed animals by 45%. With the HPF-diet nicotinic acid (200 mg/kg) is inactive. Terbufibrol lowers HDL, HDL-TC, LDL, LDL-TC and LDL-TC/PL in animals fed HPF-diet. A greater decrease of LDL-TC occurres with increasing dose. The main effect of Clofibrate (200 mg/kg) is to reduce HDL and HDL-TC and to increase LDL.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    56488-59-6
  • Formula Weight
    344.4
  • Molecular Formula
    C20H24O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(CC(COC1=CC=C(C(O)=O)C=C1)O)C2=CC=C(C(C)(C)C)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Howard AN, et al. The hypocholesterolemic effect of terbufibrol and other drugs in normal and hypercholesterolemic baboons. Atherosclerosis. 1979 Apr;32(4):367-80.?
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