
Terbufibrol
CAS No. 56488-59-6
Terbufibrol( —— )
Catalog No. M33239 CAS No. 56488-59-6
Terbufibrol reduces the levels of serum total cholesterol in normal and hypercholesterolemic male rats.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 260 | Get Quote |
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5MG | 319 | Get Quote |
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10MG | 540 | Get Quote |
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25MG | 840 | Get Quote |
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50MG | 1132 | Get Quote |
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100MG | 1512 | Get Quote |
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500MG | 3024 | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameTerbufibrol
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NoteResearch use only, not for human use.
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Brief DescriptionTerbufibrol reduces the levels of serum total cholesterol in normal and hypercholesterolemic male rats.
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DescriptionTerbufibrol has been shown highly active in reducing serum total cholesterol (TC) levels in the normal and hypercholesterolemic male rat.
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In Vitro——
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In VivoTerbufibrol (20-200 mg/kg) is active in lowering serum TC in animals on all 3 diets, but the extent of cholesterol reduction varies in the order cholesterol (HC)>high protein and fat diet (HPF)>N (max. reductions: 154, 80, and 70%, respectively). Clofibrate (200 mg/kg) decreases TC by a maximum of 28% with the HPF-diet and 13% with the N-diet but is inactive with the HC-diet. Cholestyramine (400 mg/kg/day) is inactive in HPF-fed animals but reduces TC in HC-fed animals by 45%. With the HPF-diet nicotinic acid (200 mg/kg) is inactive. Terbufibrol lowers HDL, HDL-TC, LDL, LDL-TC and LDL-TC/PL in animals fed HPF-diet. A greater decrease of LDL-TC occurres with increasing dose. The main effect of Clofibrate (200 mg/kg) is to reduce HDL and HDL-TC and to increase LDL.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number56488-59-6
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Formula Weight344.4
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Molecular FormulaC20H24O5
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Purity>98% (HPLC)
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Solubility——
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SMILESO(CC(COC1=CC=C(C(O)=O)C=C1)O)C2=CC=C(C(C)(C)C)C=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Howard AN, et al. The hypocholesterolemic effect of terbufibrol and other drugs in normal and hypercholesterolemic baboons. Atherosclerosis. 1979 Apr;32(4):367-80.?
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