Tenovin-6

CAS No. 1011557-82-6

Tenovin-6 ( —— )

Catalog No. M10073 CAS No. 1011557-82-6

Tenovin-6 is a small molecule activator of p53 transcriptional activity.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 46 In Stock
5MG 63 In Stock
10MG 80 In Stock
25MG 143 In Stock
50MG 219 In Stock
100MG 372 In Stock
500MG 881 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Tenovin-6
  • Note
    Research use only, not for human use.
  • Brief Description
    Tenovin-6 is a small molecule activator of p53 transcriptional activity.
  • Description
    Tenovin-6 is an inhibitor of SIRT1 and SIRT2, slightly inhibits HDAC8, and is also a potent activator of p53, with IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively.
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    SIRT1; SIRT2; SIRT3
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1011557-82-6
  • Formula Weight
    454.63
  • Molecular Formula
    C25H34N4O2S
  • Purity
    >98%(HPLC)
  • Solubility
    Water: 98 mg/mL warmed (215.55 mM); DMSO: 98 mg/mL (215.55 mM)
  • SMILES
    CN(C)CCCCC(=O)NC1=CC=C(NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lain S, et al. Y Cell, 2008, 13(5), 454-463.
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