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Tenovin-6
CAS No. 1011557-82-6
Tenovin-6 ( —— )
Catalog No. M10073 CAS No. 1011557-82-6
Tenovin-6 is a small molecule activator of p53 transcriptional activity.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 46 | In Stock |
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| 5MG | 63 | In Stock |
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| 10MG | 80 | In Stock |
|
| 25MG | 143 | In Stock |
|
| 50MG | 219 | In Stock |
|
| 100MG | 372 | In Stock |
|
| 500MG | 881 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTenovin-6
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NoteResearch use only, not for human use.
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Brief DescriptionTenovin-6 is a small molecule activator of p53 transcriptional activity.
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DescriptionTenovin-6 is an inhibitor of SIRT1 and SIRT2, slightly inhibits HDAC8, and is also a potent activator of p53, with IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively.
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorSIRT1; SIRT2; SIRT3
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1011557-82-6
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Formula Weight454.63
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Molecular FormulaC25H34N4O2S
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Purity>98%(HPLC)
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SolubilityWater: 98 mg/mL warmed (215.55 mM); DMSO: 98 mg/mL (215.55 mM)
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SMILESCN(C)CCCCC(=O)NC1=CC=C(NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lain S, et al. Y Cell, 2008, 13(5), 454-463.
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Tenovin-6 Hydrochlor...
Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively), and is also a potent p53 activator.
