Cart
sales@molnova.com
Home - Products - Others - Other Targets - Teglicar

Teglicar

CAS No. 250694-07-6

Teglicar ( ST-1326;ST1326 )

Catalog No. M13738 CAS No. 250694-07-6

Teglicar (ST-1326) is a potent, selective and reversible inhibitor of liver carnitine palmitoyl-transferase 1 (L-CPT1) with IC50 of 0.68 uM, Ki of 0.36 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 410 Get Quote
50MG 1539 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Teglicar
  • Note
    Research use only, not for human use.
  • Brief Description
    Teglicar (ST-1326) is a potent, selective and reversible inhibitor of liver carnitine palmitoyl-transferase 1 (L-CPT1) with IC50 of 0.68 uM, Ki of 0.36 uM.
  • Description
    Teglicar (ST-1326) is a potent, selective and reversible inhibitor of liver carnitine palmitoyl-transferase 1 (L-CPT1) with IC50 of 0.68 uM, Ki of 0.36 uM; displays an extraordinarily high selectivity (39-fold) toward the liver isoform over the heart isoform (muscle-CPT1;M-CPT1); reduces gluconeogenesis and improves glucose homeostasis, shows antiketotic and antidiabetic activity in diabetic db/db mice; also inhibits fatty acid oxidation associated with cell growth arrest, mitochondrial damage, and apoptosis induction in leukemia cell lines; orally active.Diabetes Phase 2 Discontinued
  • Synonyms
    ST-1326;ST1326
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Metabolic Disease
  • Indication
    Diabetes

Chemical Information

  • CAS Number
    250694-07-6
  • Formula Weight
    399.62
  • Molecular Formula
    C22H45N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCCCCCCCCCCCCCNC(=O)NC(CC(=O)[O-])C[N+](C)(C)C
  • Chemical Name
    (R)-4-Trimethylammonio-3-[(tetradecylcarbamoyl)amino]butyrate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ricciardi MR, et al. Blood. 2015 Oct 15;126(16):1925-9.
2. Giannessi F, et al. J Med Chem. 2003 Jan 16;46(2):303-9.
3. Conti R, et al. Diabetes. 2011 Feb;60(2):644-51.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 1,2-Distearoyl-sn-gl...

    1,2-Distearoyl-sn-glycerol is a chemical compound.

  • 4-Acetamidobenzenesu...

    4-Acetamidobenzenesulfonyl azide is a chemical compound.

  • Z433927330

    Z433927330 is a potent and selective Aquaporin-7 (AQP7) inhibitor(IC50s of 0.2).Z433927330 inhibits glycerol permeability(IC50 : 0.6 μM).

Sign In Join Free