Tat-NR2B9c ( NA-1 )

Catalog No. M14683 CAS No. 500992-11-0

Tat-NR2B9c (NA-1) is a neuroprotective agent; exhibits high-affinity binding to the second PDZ domain of PSD-95.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Tat-NR2B9c
Note

Research use only, not for human use.
Brief Description

Tat-NR2B9c (NA-1) is a neuroprotective agent; exhibits high-affinity binding to the second PDZ domain of PSD-95.
Description

Tat-NR2B9c (NA-1) is a neuroprotective agent; exhibits high-affinity binding to the second PDZ domain of PSD-95; inhibits NR2A-NR2C/PSD-95 interactions (IC50=1-10 uM) and nNOS/PSD-95 interaction (IC50=200 nM).Stroke Phase 3 Clinical
Synonyms

NA-1
Pathway

Others
Target

Other Targets
Recptor

Other Targets
Research Area

Neurological Disease
Indication

Stroke

Chemical Information

CAS Number

500992-11-0
Formula Weight

2518.88
Molecular Formula

C105H188N42O30
Purity

>98% (HPLC)
Solubility

H2O
SMILES

CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)N
Chemical Name

L-Valine, L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-seryl-L-seryl-L-isoleucyl-L-α-glutamyl-L-seryl-L-α-aspartyl-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Cui H, et al. J Neurosci. 2007 Sep 12;27(37):9901-15.
2. Sun HS, et al. Stroke. 2008 Sep;39(9):2544-53.
3. Soriano FX, et al. J Neurosci. 2008 Oct 15;28(42):10696-710.

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