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Talniflumate
CAS No. 66898-62-2
Talniflumate ( Talniflumate )
Catalog No. M18975 CAS No. 66898-62-2
Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 40 | In Stock |
|
| 5MG | 63 | In Stock |
|
| 10MG | 88 | In Stock |
|
| 25MG | 173 | In Stock |
|
| 50MG | 284 | In Stock |
|
| 100MG | 426 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTalniflumate
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NoteResearch use only, not for human use.
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Brief DescriptionTalniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture.
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DescriptionTalniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome.
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SynonymsTalniflumate
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PathwayOthers
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TargetOther Targets
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RecptorhCLCA1/mCLCA3;COX;Cl-/HCO3- exchanger;GCNT3
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Research Area——
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Indication——
Chemical Information
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CAS Number66898-62-2
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Formula Weight414.33
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Molecular FormulaC21H13F3N2O4
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Purity98%
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Solubility——
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SMILESFC(F)(F)c1cccc(Nc2ncccc2C(=O)OC2OC(=O)c3ccccc23)c1
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Chemical Name2-[[3-(Trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid 1,3-dihydro-3-oxo-1-isobenzofuranyl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Knight D. Talniflumate (Genaera)[J]. Current Opinion in Investigational Drugs, 2004, 5(5):557-62.
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