Talniflumate

CAS No. 66898-62-2

Talniflumate ( Talniflumate )

Catalog No. M18975 CAS No. 66898-62-2

Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 40 In Stock
5MG 63 In Stock
10MG 88 In Stock
25MG 173 In Stock
50MG 284 In Stock
100MG 426 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Talniflumate
  • Note
    Research use only, not for human use.
  • Brief Description
    Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture.
  • Description
    Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome.
  • Synonyms
    Talniflumate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    hCLCA1/mCLCA3;COX;Cl-/HCO3- exchanger;GCNT3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    66898-62-2
  • Formula Weight
    414.33
  • Molecular Formula
    C21H13F3N2O4
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    FC(F)(F)c1cccc(Nc2ncccc2C(=O)OC2OC(=O)c3ccccc23)c1
  • Chemical Name
    2-[[3-(Trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid 1,3-dihydro-3-oxo-1-isobenzofuranyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Knight D. Talniflumate (Genaera)[J]. Current Opinion in Investigational Drugs, 2004, 5(5):557-62.
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