Talniflumate
CAS No. 66898-62-2
Talniflumate ( Talniflumate )
Catalog No. M18975 CAS No. 66898-62-2
Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture.
Purity : 98%
Size | Price / USD | Stock | Quantity |
2MG | 40 | In Stock |
|
5MG | 63 | In Stock |
|
10MG | 88 | In Stock |
|
25MG | 173 | In Stock |
|
50MG | 284 | In Stock |
|
100MG | 426 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTalniflumate
-
NoteResearch use only, not for human use.
-
Brief DescriptionTalniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture.
-
DescriptionTalniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome.
-
SynonymsTalniflumate
-
PathwayOthers
-
TargetOther Targets
-
RecptorhCLCA1/mCLCA3;COX;Cl-/HCO3- exchanger;GCNT3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number66898-62-2
-
Formula Weight414.33
-
Molecular FormulaC21H13F3N2O4
-
Purity98%
-
Solubility——
-
SMILESFC(F)(F)c1cccc(Nc2ncccc2C(=O)OC2OC(=O)c3ccccc23)c1
-
Chemical Name2-[[3-(Trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid 1,3-dihydro-3-oxo-1-isobenzofuranyl ester
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Parisyunnanoside B
Parisyunnanoside B is a natural product of Paris, Liliaceae. Parisyunnanoside B can be used as a reference standard.
-
tetrahydroxyl diphen...
EH-201 is a low MW inducer of erythropoietin. EH-201 induces expression of erythropoietin PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo EH-201 treatment restores memory impairment as assessed by the passive avoidance test in SD Aβ and KA mouse models.
-
Caffeoylcalleryanin
Caffeoylcalleryanin exerted strong 15-LOX inhibitory activity; IC50 values was 1.59 μM.A. pulchra leaves ethanol extract (EEAPL) affords compounds with antiviral activity, mainly against DENV-2. respectively, while Caffeoylcalleryanin was the most effective anti-DENV-2 constituent, with a SI of 20.0.