TXNIP-IN-1
CAS No. 1268955-50-5
TXNIP-IN-1 ( —— )
Catalog No. M26491 CAS No. 1268955-50-5
TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 260 | Get Quote |
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10MG | 394 | Get Quote |
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25MG | 653 | Get Quote |
|
50MG | 888 | Get Quote |
|
100MG | 1242 | Get Quote |
|
500MG | 2493 | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameTXNIP-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionTXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease.
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DescriptionTXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease.(In Vitro):In monocytes, TXNIP-IN-1 (1.25-5 μM) reduces HG-induced expression of TNF. TXNIP-IN-1 bocks high glucose (HG-induced) TXNIP-TRX complex formation. TXNIP-IN-1 (5 μM; 16-72 hours) inhibits c-TRX interaction in THP1 cells cultured in 25mM glucose. TXNIP-IN-1 targets TXNIP mRNA in human pancreatic islets. In THP1 cells, TXNIP-IN-1 (1.25-5 μM; 72 hours) inhibits TXNIP mRNA expression. TXNIP-IN-1 (0.3-10 μM; 72 hours) inhibits TXNIP mRNA expression in murine RAW macrophages. In MIN6 cells, TXNIP-IN-1 (5-20 μM; 72 hours) decreases TXNIP but not TNF-alpha mRNA levels. TXNIP-IN-1 (0.62-5 μM; 72 hours) affects TXNIP and TNF-alpha mRNA expression in the human pancreas 1.1B4 beta cells.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1268955-50-5
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Formula Weight248.2
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Molecular FormulaC12H12N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)C(N1C(=O)c2ccncc2C1=O)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Xiong Li, et al. A new cytisine-type alkaloid from the stem bark of Maackia amurensis. Nat Prod Res. 2010 Oct;24(16):1499-502.
molnova catalog
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