Cart
sales@molnova.com
TUG-469
CAS No. 1236109-67-3
TUG-469( TUG469 | TUG 469 )
Catalog No. M28019 CAS No. 1236109-67-3
TUG-469 is an effective free fatty acid 1 receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 37 | Get Quote |
|
| 10MG | 59 | Get Quote |
|
| 25MG | 112 | Get Quote |
|
| 50MG | 177 | Get Quote |
|
| 100MG | 299 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameTUG-469
-
NoteResearch use only, not for human use.
-
Brief DescriptionTUG-469 is an effective free fatty acid 1 receptor agonist.
-
DescriptionTUG-469 is an effective free fatty acid 1 receptor agonist.
-
In VitroTUG-469 (0-10 μM) shows efficacy to hFFA1 with a pEC50 value of 7.73.TUG-469 (10 μM) increases the insulin secretion under 10 mM glucose stimulation.TUG-469 (0-100 μM) is >200-fold selective for FFA1 over FFA4 with EC50 values of 19 nM and 4.4 μM for FFA1 and FFA4, respectively.TUG-469 (5 μM; 30 min) significantly increases insulin secretion of INS-1 cells with the presence of high glucose concentration (16.7 mM).
-
In VivoTUG-469 (5 mg/kg; i.p.; 60 and 90 min after glucose administration) affects blood glucose level. Animal Model:Male NZO mice with glucose administration Dosage:5 mg/kg Administration:Intraperitoneal injection; 5 mg/kg; 60 and 90 min after glucose administration Result:Reduced the blood glucose level.
-
SynonymsTUG469 | TUG 469
-
PathwayOthers
-
TargetOther Targets
-
RecptorInfluenza virus|neuroprotection|Antifection
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1236109-67-3
-
Formula Weight345.442
-
Molecular FormulaC23H23NO2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (289.49 mM)
-
SMILESCc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Jung JW, et al. Isoprenylated flavonoids from the root bark of Morus alba and their hepatoprotective and neuroprotective activities. Arch Pharm Res. 2015 Nov;38(11):2066-75.
molnova catalog
related products
-
3,7,4-Trihydroxy-5-m...
3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is a natural product.
-
GRGDSPK
GRGDSPK is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.
-
6-Methoxysalicylic a...
6-Methoxysalicylic acid may be employed as internal standard for the determination of acetylsalicylic acid (aspirin ASA) and its major metabolite salicylic acid (SA)and exhibits significant analgesic effects
