TTNPB ( TTNPB; Ro 13-7410; Ro-13-7410; Arotinoid acid )

Catalog No. M17576 CAS No. 71441-28-6

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Datasheet

HNMR

HPLC

MSDS

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Product Name

TTNPB
Note

Research use only, not for human use.
Brief Description

TTNPB, a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM), respectively.
Description

TTNPB is a selective and highly potent agonist of retinoic acid receptors (RAR) α, β, and γ.
Synonyms

TTNPB; Ro 13-7410; Ro-13-7410; Arotinoid acid
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

RARα; RARβ; RARγ; RARγ
Research Area

Cancer
Indication

——

CAS Number

71441-28-6
Formula Weight

348.48
Molecular Formula

C24H28O2
Purity

98%
Solubility

DMSO : 11.25 mg/mL. 32.28 mM;
SMILES

c12c(C(CCC2(C)C)(C)C)ccc(c1)/C(=C/c1ccc(cc1)C(=O)O)/C
Chemical Name

4-[(E)-2-(5,5,8,8-Tetramethyl-6,7-dihydronaphthalen-2-yl)prop-1-enyl]benzoic acid

1. Pignatello MA, et al. Toxicol Appl Pharmacol. 1997, 142(2), 319-327.

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