TQS
CAS No. 353483-92-8
TQS ( 4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide )
Catalog No. M24306 CAS No. 353483-92-8
TQS is a positive allosteric modulator of α7 nACh receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 43 | In Stock |
|
5MG | 68 | In Stock |
|
10MG | 110 | In Stock |
|
25MG | 237 | In Stock |
|
50MG | 383 | In Stock |
|
100MG | 565 | In Stock |
|
500MG | 1215 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTQS
-
NoteResearch use only, not for human use.
-
Brief DescriptionTQS is a positive allosteric modulator of α7 nACh receptors.
-
DescriptionTQS is a positive allosteric modulator of α7 nACh receptors.
-
Synonyms4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
-
PathwayEndocrinology/Hormones
-
TargetAChR
-
Recptorα7 nAChR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number353483-92-8
-
Formula Weight376.5
-
Molecular FormulaC22H20N2O2S
-
Purity>98% (HPLC)
-
SolubilityDMSO : 240 mg/mL?(637.50 mM;?Need ultrasonic)
-
SMILESNS(c(cc1)cc(C2C=CCC22)c1NC2c1cccc2ccccc12)(=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Muzaffar A , Sami A , Papke R L , et al. The α7 nicotinic acetylcholine receptor positive allosteric modulator attenuates lipopolysaccharide-induced activation of hippocampal IκB and CD11b gene expression in mice[J]. Drug Discoveries & Therapeutics, 2017, 11(4):206-211.
molnova catalog
related products
-
Aclidinium bromide
Aclidinium Bromide inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.
-
Pirenzepine dihydroc...
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function.
-
Benzethonium chlorid...
Bactericidal cationic quaternary ammonium surfactant used as a topical anti-infective agent.