TQS

CAS No. 353483-92-8

TQS ( 4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide )

Catalog No. M24306 CAS No. 353483-92-8

TQS is a positive allosteric modulator of α7 nACh receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 68 In Stock
10MG 110 In Stock
25MG 237 In Stock
50MG 383 In Stock
100MG 565 In Stock
500MG 1215 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TQS
  • Note
    Research use only, not for human use.
  • Brief Description
    TQS is a positive allosteric modulator of α7 nACh receptors.
  • Description
    TQS is a positive allosteric modulator of α7 nACh receptors.
  • Synonyms
    4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    α7 nAChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    353483-92-8
  • Formula Weight
    376.5
  • Molecular Formula
    C22H20N2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 240 mg/mL?(637.50 mM;?Need ultrasonic)
  • SMILES
    NS(c(cc1)cc(C2C=CCC22)c1NC2c1cccc2ccccc12)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Muzaffar A , Sami A , Papke R L , et al. The α7 nicotinic acetylcholine receptor positive allosteric modulator attenuates lipopolysaccharide-induced activation of hippocampal IκB and CD11b gene expression in mice[J]. Drug Discoveries & Therapeutics, 2017, 11(4):206-211.
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