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TP0903

CAS No. 1341200-45-0

TP0903( TP-0903; TP 0903; TP0903; Dubermatinib )

Catalog No. M11367 CAS No. 1341200-45-0

TP-0903 is a potent and selective Axl kinase inhibitor with IC50 of 27 nM.

Purity : >98%(HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
100mg	525	In stock
50mg	363	In stock
25mg	207	In stock
10mg	121	In stock
5mg	81	In stock

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Biological Information

Product Name

TP0903
Note

Research use only, not for human use.
Brief Description

TP-0903 is a potent and selective Axl kinase inhibitor with IC50 of 27 nM.
Description

TP-0903 is a potent and selective Axl kinase inhibitor with IC50 of 27 nM.
Synonyms

TP-0903; TP 0903; TP0903; Dubermatinib
Pathway

Tyrosine Kinase
Target

TAM Receptor
Recptor

AXL
Research Area

Cancer
Indication

Solid Tumors

Chemical Information

CAS Number

1341200-45-0
Formula Weight

516.06
Molecular Formula

C24H30ClN7O2S
Purity

>98%(HPLC)
Solubility

Ethanol: 6 mg/mL warmed (11.62 mM); DMSO: 7 mg/mL warmed (13.56 mM)
SMILES

O=S(C1=CC=CC=C1NC2=NC(NC3=CC=C(CN4CCN(C)CC4)C=C3)=NC=C2Cl)(N(C)C)=O
Chemical Name

2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,N-dimethylbenzenesulfonamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Feneyrolles C, et al. Mol Y Ther. 2014 Sep;13(9):2141-8.

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