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Home - Products - Wnt/Notch/Hedgehog - Wnt/beta/catenin - TNIK-IN-2

TNIK-IN-2

CAS No. 2754265-76-2

TNIK-IN-2( —— )

Catalog No. M28760 CAS No. 2754265-76-2

TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    TNIK-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.
  • Description
    TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.(In Vitro):In HCT116 cells, the IC50 value was 31.26 μM for TNIK.
  • In Vitro
    TNIK-IN-2 (compound 1) inhibits TNIK, with an IC50 of 31.26 μM in HCT116 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Wnt/beta/catenin
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2754265-76-2
  • Formula Weight
    373.4
  • Molecular Formula
    C22H19N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1cccc(NC(c(ccc(-c2cnc3[nH]ccc3c2)c2)c2OC)=O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kagenishi T, et al. MES Buffer Affects Arabidopsis Root Apex Zonation and Root Growth by Suppressing Superoxide Generation in Root Apex. Front Plant Sci. 2016;7:79. Published 2016 Feb 18.
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