TMS

CAS No. 24144-92-1

TMS ( 2,3',4,5'-Tetramethoxystilbene )

Catalog No. M13695 CAS No. 24144-92-1

TMS is a very selective and potent competitive inhibitor of P450 1B1 (CYP1A1). It has strong selectivity among P450 family 1 enzymes.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 42 In Stock
10MG 69 In Stock
25MG 138 In Stock
50MG 251 In Stock
100MG 374 In Stock
500MG 848 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TMS
  • Note
    Research use only, not for human use.
  • Brief Description
    TMS is a very selective and potent competitive inhibitor of P450 1B1 (CYP1A1). It has strong selectivity among P450 family 1 enzymes.
  • Description
    TMS is a very selective and potent competitive inhibitor of P450 1B1 (CYP1A1). It has strong selectivity among P450 family 1 enzymes. TMS exhibits 50-fold selectivity for P450 1B1 over P4501A1 and 500-fold selectivity for P450 1B1 over P450 1A2.
  • Synonyms
    2,3',4,5'-Tetramethoxystilbene
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    CYP450 1B1
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    24144-92-1
  • Formula Weight
    300.35
  • Molecular Formula
    C18H20O4
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    COC1=CC(OC)=CC(/C=C/C2=CC=C(OC)C=C2OC)=C1
  • Chemical Name
    (E)-1-(3,5-dimethoxystyryl)-2,4-dimethoxybenzene

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Einem Lindeman T,et al. The resveratrol analogue, 2,3',4,5'-tetramethoxystilbene, does not inhibit CYP gene expression, enzyme activity and benzoapyrene-Dna adduct formation in MCF-7 cells exposed to benzoapyrene. Mutagenesis. 2011 Sep;26(5):629-35.
molnova catalog
related products
  • Rhodionin

    Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administered drugs; they can significantly suppress the elevation of the postprandial blood triglyceride level suggests that they may be to the treatment of lifestyle-related diseases such as hyperlipidemia and exogeneous obesity and to health foods.

  • 2,6-Dimethylquinolin...

    2,6-Dimethylquinoline is a natural product extracted from the roots of Peucedantu praeruptorum. 2,6-Dimethylquinoline is an inhibitor of CYP1A2 and CYP2B6 with an IC50 of 3.3 and 480 μM, respectively.

  • Tienilic Acid

    Tienilic Acid is a uricosuric diuretic with certain hepatotoxicity.