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TM5441
CAS No. 1190221-43-2
TM5441 ( TM-5441;BMS790052; EBP883 )
Catalog No. M17864 CAS No. 1190221-43-2
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor 1 (PAI-1).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 43 | In Stock |
|
| 5MG | 71 | In Stock |
|
| 10MG | 110 | In Stock |
|
| 25MG | 237 | In Stock |
|
| 50MG | 444 | In Stock |
|
| 100MG | 631 | In Stock |
|
| 500MG | 1314 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTM5441
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NoteResearch use only, not for human use.
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Brief DescriptionTM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor 1 (PAI-1).
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DescriptionTM-5441, also known as EBP 883 and BMS-790052, is a potent plasminogen activator inhibitor-1 (PAI-1). TM-5441 inhibits several tumor cell lines with IC50 values between 9.7 and 60.3 μM. TM5441 protects against high-fat diet-induced obesity and adipocyte injury in mice.
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SynonymsTM-5441;BMS790052; EBP883
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PathwayOthers
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TargetOther Targets
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RecptorPAI-1
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Research Area——
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Indication——
Chemical Information
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CAS Number1190221-43-2
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Formula Weight428.83
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Molecular FormulaC21H17ClN2O6
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Purity98%
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SolubilityDMSO : ≥ 300 mg/mL; 699.59 mM
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SMILESO=C(O)c3cc(Cl)ccc3NC(=O)COCC(=O)Nc1cccc(c1)c2ccco2
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Chemical Name5-chloro-2-(2-(2-((3-(furan-3-yl)phenyl)amino)-2-oxoethoxy)acetamido)benzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Placencio VR, et al. Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity. PLoS One. 2015 Jul 24;10(7):e0133786.
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