Cart
sales@molnova.com
Home - Products - Others - Other Targets - TLR1

TLR1

CAS No. 566914-00-9

TLR1( —— )

Catalog No. M24556 CAS No. 566914-00-9

TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 267 In Stock
10MG 408 In Stock
25MG 660 In Stock
50MG 888 In Stock
100MG 1224 In Stock
500MG 2448 In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    TLR1
  • Note
    Research use only, not for human use.
  • Brief Description
    TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.
  • Description
    TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.
  • In Vitro
    TLR1 inhibits IL-1β-induced phosphorylation of the mitogen-activated protein kinase p38 in EL4 thymoma cells and in freshly isolated murine lymphocytes in a concentration-dependent manner.
  • In Vivo
    TLR1 interferes with the interactions between mouse MyD88 and IL-1RI at the TIR domains. TLR1 produces a significant attenuation of the IL-1β-induced fever response (200 mg/kg, i.p.).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    566914-00-9
  • Formula Weight
    302.41
  • Molecular Formula
    C18H26N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC(C)[C@@H](C(=O)N1CCCC1)NC(=O)CCC2=CC=CC=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bartfai T, et al. A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7971-6.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Skimmianin

    Skimmianin is a spasmolytic agent. Skimmianin shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.

  • XYLOTRIOSE

    XYLOTRIOSE is a natural xylooligosaccharide acts as a bifidogenic factor.

  • Citrusin C

    Citrusin is a useful organic compound for research related to life sciences.

Sign In Join Free