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TG100713
CAS No. 925705-73-3
TG100713( TG100713 )
Catalog No. M17665 CAS No. 925705-73-3
TG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
|
| 5MG | 50 | In Stock |
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| 10MG | 80 | In Stock |
|
| 25MG | 160 | In Stock |
|
| 50MG | 302 | In Stock |
|
| 100MG | 444 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTG100713
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NoteResearch use only, not for human use.
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Brief DescriptionTG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.
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DescriptionTG100713 is an inhibitor of PI3-kinase (IC50 values are 24, 50, 165 and 215 nM for PI3Kδ, γ, α and β isoforms respectively). Inhibits endothelial cell proliferation.
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In VitroTG100713 (10 μM; 48 or 72 h) strongly inhibits endothelial cell (EC) proliferation.
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In Vivo——
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SynonymsTG100713
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PathwayCell Cycle/DNA Damage
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TargetROCK
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RecptorPI3Kδ , PI3Kγ , PI3Kα , PI3Kβ
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number925705-73-3
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Formula Weight254.25
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Molecular FormulaC12H10N6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 6.41 mg/mL (25.21 mM)
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SMILESC1=CC(=CC(=C1)O)C2=CN=C3C(=N2)C(=NC(=N3)N)N
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Chemical Name3-(2,4-diaminopteridin-6-yl)phenol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Doukas J et al. Proc Natl Acad Sci U S A, 2006, 103(52), 19866-19871.
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