TES-1025

CAS No. 1883602-21-8

TES-1025 ( —— )

Catalog No. M26841 CAS No. 1883602-21-8

TES-1025 is an effective and selective inhibitor of human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (IC50: 13 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 52 In Stock
10MG 71 In Stock
25MG 110 In Stock
50MG 157 In Stock
100MG 229 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TES-1025
  • Note
    Research use only, not for human use.
  • Brief Description
    TES-1025 is an effective and selective inhibitor of human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (IC50: 13 nM).
  • Description
    TES-1025 is an effective and selective inhibitor of human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (IC50: 13 nM).(In Vitro):TES-1025 increases NAD+ levels in cellular systems.(In Vivo):TES-1025 (0.5 mg/kg; i.v.) shows low blood clearance, with low volumes of distribution and half-lives of about 5.33 h, although the blood concentration of TES-1025 (5 mg/kg) is quantifiable for up to 8 h after oral administration. A good systemic exposure is recorded for TES-1025, with a Cmax of 2570 ng/mL reaches at 2 h. The greater oral exposure of TES-1025 is AUC0-8h of 19?200 h?ng/mL and 36?600 h?ng/mL, respectively.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SGLT2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1883602-21-8
  • Formula Weight
    383.4
  • Molecular Formula
    C18H13N3O3S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)Cc1cccc(CSc2nc(-c3cccs3)c(C#N)c(=O)[nH]2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Global Diabetes Pipeline Landscape Report 2020 Featuring Daewoong's Enavogliflozin & Janssen Biotech's Golimumab Among Others - ResearchAndMarkets.com
molnova catalog
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