TES-1025
CAS No. 1883602-21-8
TES-1025 ( —— )
Catalog No. M26841 CAS No. 1883602-21-8
TES-1025 is an effective and selective inhibitor of human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (IC50: 13 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 52 | In Stock |
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10MG | 71 | In Stock |
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25MG | 110 | In Stock |
|
50MG | 157 | In Stock |
|
100MG | 229 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameTES-1025
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NoteResearch use only, not for human use.
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Brief DescriptionTES-1025 is an effective and selective inhibitor of human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (IC50: 13 nM).
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DescriptionTES-1025 is an effective and selective inhibitor of human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (IC50: 13 nM).(In Vitro):TES-1025 increases NAD+ levels in cellular systems.(In Vivo):TES-1025 (0.5 mg/kg; i.v.) shows low blood clearance, with low volumes of distribution and half-lives of about 5.33 h, although the blood concentration of TES-1025 (5 mg/kg) is quantifiable for up to 8 h after oral administration. A good systemic exposure is recorded for TES-1025, with a Cmax of 2570 ng/mL reaches at 2 h. The greater oral exposure of TES-1025 is AUC0-8h of 19?200 h?ng/mL and 36?600 h?ng/mL, respectively.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorSGLT2
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Research Area——
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Indication——
Chemical Information
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CAS Number1883602-21-8
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Formula Weight383.4
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Molecular FormulaC18H13N3O3S2
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Purity>98% (HPLC)
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Solubility——
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SMILESOC(=O)Cc1cccc(CSc2nc(-c3cccs3)c(C#N)c(=O)[nH]2)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Global Diabetes Pipeline Landscape Report 2020 Featuring Daewoong's Enavogliflozin & Janssen Biotech's Golimumab Among Others - ResearchAndMarkets.com
molnova catalog
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