TED-347
CAS No. 2378626-29-8
TED-347 ( —— )
Catalog No. M21960 CAS No. 2378626-29-8
TED-347 is an?irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 104 | In Stock |
|
10MG | 177 | In Stock |
|
25MG | 357 | In Stock |
|
50MG | 537 | In Stock |
|
100MG | 781 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameTED-347
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NoteResearch use only, not for human use.
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Brief DescriptionTED-347 is an?irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
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DescriptionTED-347 is an?irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorTEAD4-Yap1
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Research Area——
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Indication——
Chemical Information
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CAS Number2378626-29-8
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Formula Weight313.7
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Molecular FormulaC15H11ClF3NO
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Purity>98% (HPLC)
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SolubilityDMSO:64 mg/ml(204.02 mM)
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SMILESFC(F)(F)c1cccc(Nc2ccccc2C(=O)CCl)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Khuchtumur Bum-Erdene, et al. Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD?Yap Protein-Protein Interaction. Cell Chem Biol. 2019 Mar 21;26(3):378-389.e13.
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