TED-347

CAS No. 2378626-29-8

TED-347 ( —— )

Catalog No. M21960 CAS No. 2378626-29-8

TED-347 is an?irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 104 In Stock
10MG 177 In Stock
25MG 357 In Stock
50MG 537 In Stock
100MG 781 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    TED-347
  • Note
    Research use only, not for human use.
  • Brief Description
    TED-347 is an?irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
  • Description
    TED-347 is an?irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TEAD4-Yap1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2378626-29-8
  • Formula Weight
    313.7
  • Molecular Formula
    C15H11ClF3NO
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:64 mg/ml(204.02 mM)
  • SMILES
    FC(F)(F)c1cccc(Nc2ccccc2C(=O)CCl)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Khuchtumur Bum-Erdene, et al. Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD?Yap Protein-Protein Interaction. Cell Chem Biol. 2019 Mar 21;26(3):378-389.e13.
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