TD-198946 ( TD-198946; TD 198946; TD198946 )

Catalog No. M17496 CAS No. 364762-86-7

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Product Name

TD-198946
Note

Research use only, not for human use.
Brief Description

TD-198946, a potent chondrogenic agent, is a thienoindazole derivative.
Description

TD-198946 is a thienoindazole derivative, has been found to be active in the studies as a chondrogenic factor. Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration. A novel disease-modifying osteoarthritis drug candidate targeting Runx1.
Synonyms

TD-198946; TD 198946; TD198946
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

CAS Number

364762-86-7
Formula Weight

482.55
Molecular Formula

C27H22N4O3S
Purity

98%
Solubility

DMSO : ≥ 28 mg/mL; 58.03 mM
SMILES

Cn1c2c(CCc3c(sc(c23)Oc2ccc(cc2)OCc2nc3ccccc3cc2)C(=O)N)cn1
Chemical Name

1-Methyl-8-[4-(quinolin-2-ylmethoxy)phenoxy]-4,5-dihydrothieno[3,4-g]indazole-6-carboxamide

1.Yano F, et al. A novel disease-modifying osteoarthritis drug candidate targeting Runx1. Ann Rheum Dis. 2013 May;72(5):748-53.

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