TD-165
CAS No. 2305936-56-3
TD-165 ( —— )
Catalog No. M27017 CAS No. 2305936-56-3
TD-165 is a PROTAC-based cereblon (CRBN) degrader comprising a?CRBN?ligand binding group, a linker and a?VHL binding group.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 260 | Get Quote |
|
10MG | 430 | Get Quote |
|
25MG | 710 | Get Quote |
|
50MG | 972 | Get Quote |
|
100MG | 1332 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTD-165
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NoteResearch use only, not for human use.
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Brief DescriptionTD-165 is a PROTAC-based cereblon (CRBN) degrader comprising a?CRBN?ligand binding group, a linker and a?VHL binding group.
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DescriptionTD-165 is a PROTAC-based cereblon (CRBN) degrader comprising a?CRBN?ligand binding group, a linker and a?VHL binding group.(In Vitro):Administration of 0.1-10?μM TD-165 for 24 hours resulted in a concentration-dependent decrease in CRBN protein levels in HEK293T cells. Administration of 0-100 nM TD-165 for 24 hours showed a 50% degradation concentration (DC50) of 20.4?nM and a maximum degradation (Dmax) value of 99.6%.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorBacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number2305936-56-3
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Formula Weight870.1
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Molecular FormulaC46H59N7O8S
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Purity>98% (HPLC)
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Solubility——
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SMILESCc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCNc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)C(C)(C)C)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.XiaoyeGeng, et al. Design and fabrication of reversible thermochromic microencapsulated phase change materials for thermal energy storage and its antibacterial activity. Energy. Volume 159, 15 September 2018, Pages 857-869.
molnova catalog
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