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TCA-1

CAS No. 864941-32-2

TCA-1 ( TCA1 )

Catalog No. M16276 CAS No. 864941-32-2

A small molecule with activity against drug-resistant and persistent tuberculosis; shows bactericidal activity against nonreplicating Mtb in vitro and is efficacious in acute and chronic Mtb infection mouse models.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 57 In Stock
5MG 87 In Stock
10MG 140 In Stock
25MG 258 In Stock
50MG 394 In Stock
100MG 584 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    TCA-1
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule with activity against drug-resistant and persistent tuberculosis; shows bactericidal activity against nonreplicating Mtb in vitro and is efficacious in acute and chronic Mtb infection mouse models.
  • Description
    A small molecule with activity against drug-resistant and persistent tuberculosis; shows bactericidal activity against nonreplicating Mtb in vitro and is efficacious in acute and chronic Mtb infection mouse models; down-regulates genes known to be involved in Mtb persistence; inhibits DprE1 and MoeW, enzymes involved in cell wall and molybdenum cofactor biosynthesis.
  • Synonyms
    TCA1
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    864941-32-2
  • Formula Weight
    375.42
  • Molecular Formula
    C16H13N3O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: Soluble （ < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    CCOC(=O)NC(=O)C1=C(SC=C1)NC(=O)C2=NC3=CC=CC=C3S2
  • Chemical Name
    ethyl (2-(benzo[d]thiazole-2-carboxamido)thiophene-3-carbonyl)carbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang F, et al. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2510-7.
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