TC-O9311

CAS No. 444932-31-4

TC-O9311( TC-O 9311 | TC-O-9311 | TC-O9311 | TCO 9311 | TCO-9311 | TCO9311 )

Catalog No. M24406 CAS No. 444932-31-4

TC-O9311 is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 63 In Stock
10MG 96 In Stock
25MG 174 In Stock
50MG 298 In Stock
100MG 446 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TC-O9311
  • Note
    Research use only, not for human use.
  • Brief Description
    TC-O9311 is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139).
  • Description
    TC-O9311 is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    TC-O 9311 | TC-O-9311 | TC-O9311 | TCO 9311 | TCO-9311 | TCO9311
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    GPR
  • Recptor
    GPR139
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    444932-31-4
  • Formula Weight
    365.39
  • Molecular Formula
    C20H19N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (342.11 mM; Need ultrasonic)
  • SMILES
    O=C(NNC(NC1=C2C=CC=CC2=CC=C1)=O)C3=CC(OC)=CC(OC)=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shi F, Shen JK, Chen D, Fog K, Thirstrup K, Hentzer M, Karlsson JJ, Menon V, Jones KA, Smith KE, Smith G. Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139. ACS Med Chem Lett. 2011 Feb 28;2(4):303-6. doi: 10.1021/ml100293q. eCollection 2011 Apr 14. PubMed PMID: 24900311; PubMed Central PMCID: PMC4028000.
molnova catalog
related products
  • MS21570

    MS21570 as a GPR171 antagonist based on its ability to blockwith an?IC50?of 220 Nmthat reduces anxiety-like behavior and fear conditioning in mice.

  • MK-6892

    MK-6892 is a selective and full agonist for the high-affinity nicotinic acid receptor GPR109A (Ki: 4 nM; GTPγS EC50: 16 nM).MK-6892 evokes a potent internalization of GPR109A in U2OS β-arrestin2-RrGFP cells.MK-6892 shows an EC50 value of 74 nM on calcium mobilization assay.

  • BTB09089

    BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production in T cells and macrophages.