TC-AQP1-1

CAS No. 37710-81-9

TC-AQP1-1( —— )

Catalog No. M27798 CAS No. 37710-81-9

TC-AQP1-1 is a blocker of the aquaporin 1 channel identified by virtual screening and inhibits water flux through hAQP1 in Xenopus laevis oocyte swelling assays at low micromolar concentrations.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 53 Get Quote
10MG 87 Get Quote
25MG 177 Get Quote
50MG 284 Get Quote
100MG 447 Get Quote
500MG 972 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    TC-AQP1-1
  • Note
    Research use only, not for human use.
  • Brief Description
    TC-AQP1-1 is a blocker of the aquaporin 1 channel identified by virtual screening and inhibits water flux through hAQP1 in Xenopus laevis oocyte swelling assays at low micromolar concentrations.
  • Description
    TC-AQP1-1 is a blocker of the aquaporin 1 channel identified by virtual screening and inhibits water flux through hAQP1 in Xenopus laevis oocyte swelling assays at low micromolar concentrations.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    mGluR5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    37710-81-9
  • Formula Weight
    218.21
  • Molecular Formula
    C12H10O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (229.14 mM)
  • SMILES
    O=C(O)/C=C/C1=CC=CC(/C=C/C(O)=O)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hill MD, et al. Development of 1H-Pyrazolo[3,4-b]pyridines as Metabotropic Glutamate Receptor 5 Positive Allosteric Modulators. ACS Med Chem Lett. 2016 Oct 3;7(12):1082-1086.
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