Cart
sales@molnova.com
TBB
CAS No. 17374-26-4
TBB ( NSC 231634; Tetrabromobenzotriazole )
Catalog No. M12636 CAS No. 17374-26-4
TBB(NSC 231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively).
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
|
| 10MG | 49 | In Stock |
|
| 25MG | 77 | In Stock |
|
| 50MG | 124 | In Stock |
|
| 100MG | 188 | In Stock |
|
| 200MG | 293 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTBB
-
NoteResearch use only, not for human use.
-
Brief DescriptionTBB(NSC 231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively).
-
DescriptionTBB(NSC 231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively).
-
SynonymsNSC 231634; Tetrabromobenzotriazole
-
PathwayAngiogenesis
-
TargetCDK
-
RecptorCK2; CDK2; GSK-3β
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number17374-26-4
-
Formula Weight434.71
-
Molecular FormulaC6HBr4N3
-
Purity>98%(HPLC)
-
SolubilityDMSO, Ethanol: 100 mM
-
SMILESBrC1=C(NN=N2)C2=C(Br)C(Br)=C1Br
-
Chemical Name4,5,6,7-tetrabromo-1H-benzo[d][1,2,3]triazole
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Orzechowska E, et al. Oncol Rep. 2012 Jan;27(1):281-5.
molnova catalog
related products
-
Voruciclib
A potent, selective and orally bioavailable CDK9 inhibitor with Ki of 0.63 nM and 1.68 nM for CDK9/cyclinT2 and CDK9/cyclinT1, respectively.
-
THZ2
THZ2, an analogue of THZ1 with improved pharmacokinetic features, is a potent, selective CDK7 inhibitor with IC50 of 13.9 nM, displays a 5-fold improved half-life in vivo compared with THZ1.
-
Kenpaullone
Kenpaullone (9-Bromopaullone,NSC-664704) is a potent inhibitor of CDK1/cyclin B with IC50 of 0.4 uM, also inhibited CDK2/cyclin A (IC50=0.68 uM), CDK2/cyclin E (IC50-7.5 uM) and CDK5/p25 (IC50=0.85 uM).
