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TBB

CAS No. 17374-26-4

TBB ( NSC 231634; Tetrabromobenzotriazole )

Catalog No. M12636 CAS No. 17374-26-4

TBB(NSC 231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively).

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    TBB
  • Note
    Research use only, not for human use.
  • Brief Description
    TBB(NSC 231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively).
  • Description
    TBB(NSC 231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively).
  • Synonyms
    NSC 231634; Tetrabromobenzotriazole
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    CK2; CDK2; GSK-3β
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    17374-26-4
  • Formula Weight
    434.71
  • Molecular Formula
    C6HBr4N3
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO, Ethanol: 100 mM
  • SMILES
    BrC1=C(NN=N2)C2=C(Br)C(Br)=C1Br
  • Chemical Name
    4,5,6,7-tetrabromo-1H-benzo[d][1,2,3]triazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Orzechowska E, et al. Oncol Rep. 2012 Jan;27(1):281-5.
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