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TASP0382088
CAS No. 1253941-85-3
TASP0382088( TASP-0382088 )
Catalog No. M11022 CAS No. 1253941-85-3
A potent, selective ALK5 inhibitor with IC50 of 4.8 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameTASP0382088
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective ALK5 inhibitor with IC50 of 4.8 nM.
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DescriptionA potent, selective ALK5 inhibitor with IC50 of 4.8 nM, >100-fold selectivity over 95 different kinases; inhibits TGF-β-induced Smad2/3 phosphorylation at cellular level with IC50 of 17 nM, inhibits Smad2 phosphorylation in mouse skin after topical application.
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In Vitro——
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In Vivo——
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SynonymsTASP-0382088
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PathwayTGF-beta/Smad
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TargetTGFBR
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RecptorTGFBR
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Research Area——
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Indication——
Chemical Information
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CAS Number1253941-85-3
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Formula Weight328.408
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Molecular FormulaC15H12N4OS2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name7-Methoxy-6-[4-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-5-yl]-1,3-benzothiazole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Amada H, et al. Chem Pharm Bull (Tokyo). 2013;61(3):286-91.
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