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TAMRA-PEG3-Azide
CAS No. 1228100-59-1
TAMRA-PEG3-Azide( —— )
Catalog No. M33506 CAS No. 1228100-59-1
TAMRA-PEG3-Azide is a TAMRA red fluorescent dye linker with a maximum excitation/emission wavelength of 553/575 nm.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 217 | Get Quote |
|
| 5MG | 269 | Get Quote |
|
| 10MG | 432 | Get Quote |
|
| 25MG | 674 | Get Quote |
|
| 50MG | 908 | Get Quote |
|
| 100MG | 1224 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTAMRA-PEG3-Azide
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NoteResearch use only, not for human use.
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Brief DescriptionTAMRA-PEG3-Azide is a TAMRA red fluorescent dye linker with a maximum excitation/emission wavelength of 553/575 nm.
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DescriptionTAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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RecptorPROTAC Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number1228100-59-1
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Formula Weight630.69
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Molecular FormulaC33H38N6O7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?Methanol : 12.5 mg/mL (19.82 mM; Ultrasonic)
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SMILES[N-]=[N+]=NCCOCCOCCOCCNC(=O)C=1C=CC(=C(C1)C(=O)[O-])C=2C=3C=CC(=CC3[O+]=C4C=C(C=CC42)N(C)C)N(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
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