Synephrine

Research use only, not for human use.

Sympathetic alpha-adrenergic agonist with actions like phenylephrine.

Sympathetic alpha-adrenergic agonist with actions like PHENYLEPHRINE. It is used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.(In Vivo):Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine.

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Animal Model:Portal vein ligation (PVL) or bile duct ligation (BDL) rats Dosage:1 mg/kg per 12 hours Administration:Oral gavage; for 8 days Result:The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index were significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance were enhanced.

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Endocrinology/Hormones

Adrenergic Receptor

Adrenergic Receptor

Other Indications

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94-07-5

167.21

C9H13NO2

>98% (HPLC)

Ethanol: 2 mg/mL warmed (11.96 mM); DMSO: 33 mg/mL warmed (197.35 mM)

CNCC(O)C1=CC=C(O)C=C1

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(-20℃)

With Ice Pack

≥ 2 years