Synephrine( —— )

Catalog No. M16729 CAS No. 94-07-5

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Product Name

Synephrine
Note

Research use only, not for human use.
Brief Description

Sympathetic alpha-adrenergic agonist with actions like phenylephrine.
Description

Sympathetic alpha-adrenergic agonist with actions like PHENYLEPHRINE. It is used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.(In Vivo):Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine.
In Vitro

——
In Vivo

Animal Model:Portal vein ligation (PVL) or bile duct ligation (BDL) rats Dosage:1 mg/kg per 12 hours Administration:Oral gavage; for 8 days Result:The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index were significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance were enhanced.
Synonyms

——
Pathway

Endocrinology/Hormones
Target

Adrenergic Receptor
Recptor

Adrenergic Receptor
Research Area

Other Indications
Indication

——

CAS Number

94-07-5
Formula Weight

167.21
Molecular Formula

C9H13NO2
Purity

>98% (HPLC)
Solubility

Ethanol: 2 mg/mL warmed (11.96 mM); DMSO: 33 mg/mL warmed (197.35 mM)
SMILES

CNCC(O)C1=CC=C(O)C=C1
Chemical Name

——

1.Hong NY, et al. Biochem Biophys Res Commun, 2012, 418(4), 720-724.

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