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Sulforaphene
CAS No. 592-95-0
Sulforaphene( —— )
Catalog No. M21772 CAS No. 592-95-0
Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 40 | In Stock |
|
| 5MG | 65 | In Stock |
|
| 10MG | 110 | In Stock |
|
| 25MG | 215 | In Stock |
|
| 50MG | 320 | In Stock |
|
| 100MG | 474 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSulforaphene
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NoteResearch use only, not for human use.
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Brief DescriptionSulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M.
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DescriptionSulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.
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In VitroWestern Blot Analysis Cell Line:HepG2 and Hep3B cell Concentration:0-40 μM Incubation Time:48 h Result:Increased Bax expression and reduced Bcl-2 expression.Inhibited expression of NF-??B-dependent genes (COX-2, iNos, and cyclinD1).
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In VivoAnimal Model:Mouse HCT116 xenograft model Dosage:1 and 5 mg/kg Administration:i.p., everyday Result:Inhibited tumor growth, and increased CDK1, MK2, and p38 phosphorylation.
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number592-95-0
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Formula Weight175.27
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Molecular FormulaO=S(/C=C/CCN=C=S)C
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL (570.55 mM; Need ultrasonic)
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SMILESO=S(/C=C/CCN=C=S)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kuang P, et al. Separation and purification of sulforaphene from radish seeds using macroporous resin and preparative high-performance liquid chromatography. Food Chem. 2013 Jan 15;136(2):342-7.
2. Anita M. Brinker, et al. Herbicidal activity of sulforaphene from stock (Matthiola incana). Journal of Chemical Ecology. Vol. 19. No. 10, 1993.
3. Mondal A, et al. Sulforaphene promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation. General Physiology and Biophysics, 27 Nov 2015, 35(1):25-34.
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