Cart
sales@molnova.com
Home - Products - Apoptosis - Apoptosis - Sulforaphene

Sulforaphene

CAS No. 592-95-0

Sulforaphene( —— )

Catalog No. M21772 CAS No. 592-95-0

Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 40 In Stock
5MG 65 In Stock
10MG 110 In Stock
25MG 215 In Stock
50MG 320 In Stock
100MG 474 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Sulforaphene
  • Note
    Research use only, not for human use.
  • Brief Description
    Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M.
  • Description
    Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.
  • In Vitro
    Western Blot Analysis Cell Line:HepG2 and Hep3B cell Concentration:0-40 μM Incubation Time:48 h Result:Increased Bax expression and reduced Bcl-2 expression.Inhibited expression of NF-??B-dependent genes (COX-2, iNos, and cyclinD1).
  • In Vivo
    Animal Model:Mouse HCT116 xenograft model Dosage:1 and 5 mg/kg Administration:i.p., everyday Result:Inhibited tumor growth, and increased CDK1, MK2, and p38 phosphorylation.
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    592-95-0
  • Formula Weight
    175.27
  • Molecular Formula
    O=S(/C=C/CCN=C=S)C
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL (570.55 mM; Need ultrasonic)
  • SMILES
    O=S(/C=C/CCN=C=S)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kuang P, et al. Separation and purification of sulforaphene from radish seeds using macroporous resin and preparative high-performance liquid chromatography. Food Chem. 2013 Jan 15;136(2):342-7. 2. Anita M. Brinker, et al. Herbicidal activity of sulforaphene from stock (Matthiola incana). Journal of Chemical Ecology. Vol. 19. No. 10, 1993. 3. Mondal A, et al. Sulforaphene promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation. General Physiology and Biophysics, 27 Nov 2015, 35(1):25-34.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Sandalore

    Sandalore prolongs human hair growth by decreasing apoptosis and increasing the production of the anagen-prolonging growth factor IGF-1 in the outer root sheath. Sandalore is a selective agonist of olfactory receptor OR2AT4.

  • Lirentelimab

    Lirentelimab (AK002) is a humanized anti-sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) antibody that induces apoptosis of IL-5-activated eosinophils and inhibits IL-5-mediated mast cell activation, and is used in the study of refractory inert systemic mastocytosis and allergic conjunctivitis.

  • Alexidine dihydrochl...

    Alexidine dihydrochloride has antifungal and antibiofilm activity against a diverse range of fungal pathogens.

Sign In Join Free