Cart
sales@molnova.com
Home - Products - Others - Other Targets - Sulfopin

Sulfopin

CAS No. 2451481-08-4

Sulfopin( PIN1-3 )

Catalog No. M24127 CAS No. 2451481-08-4

Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 In Stock
5MG 68 In Stock
10MG 113 In Stock
25MG 233 In Stock
50MG 375 In Stock
100MG 560 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Sulfopin
  • Note
    Research use only, not for human use.
  • Brief Description
    Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
  • Description
    Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
  • In Vitro
    Cell Proliferation Assay Cell Line:Kuramochi, MDA-MB-468, NGP, NBL-S, MDA-MB-468 cells Concentration:1, 2.5 μM Incubation Time:4,6, 8 days Result:Showed variation in antiproliferative effects across cancer cell lines Kuramochi, MDA-MB-468, NGP and NBL-S, with the most pronounced sensitivity observed in MDA-MB-468 cells.
  • In Vivo
    ——
  • Synonyms
    PIN1-3
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Pin1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2451481-08-4
  • Formula Weight
    281.8
  • Molecular Formula
    C11H20ClNO3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 90 mg/mL (319.38 mM; Need ultrasonic)
  • SMILES
    O=C(N(CC(C)(C)C)C(CC1)CS1(=O)=O)CCl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Dubiella C , Pinch B J , Koikawa K , et al. Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo[J]. Nature Chemical Biology.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • SCH900776 S-isomer

    SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).

  • Cichoriin

    Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumor in rats.

  • [Ala5, β-Ala8]-Neuro...

    (β-Ala8)-Neurokinin A (4-10), a neuropeptide, is a potent and selective NK-2 tachykinin receptor (Neurokinin Receptor) agonist.

Sign In Join Free