Su1498

Research use only, not for human use.

SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM).

SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.

SU-1498; SU 1498; SU1498; Tyrphostin SU 1498

Others

Other Targets

VEGFR2

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168835-82-3

390.53

C25H30N2O2

98%

DMSO : ≥ 150 mg/mL. 384.10 mM

O=C(/C(=C/c1cc(C(C)C)c(O)c(C(C)C)c1)/C#N)NCCCc1ccccc1

(2E)-2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-2-propenamide

(-20℃)

With Ice Pack

≥ 2 years