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Su1498
CAS No. 168835-82-3
Su1498 ( SU-1498; SU 1498; SU1498; Tyrphostin SU 1498 )
Catalog No. M17363 CAS No. 168835-82-3
SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 42 | In Stock |
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| 5MG | 65 | In Stock |
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| 10MG | 110 | In Stock |
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| 25MG | 210 | In Stock |
|
| 50MG | 311 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSu1498
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NoteResearch use only, not for human use.
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Brief DescriptionSU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM).
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DescriptionSU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.
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SynonymsSU-1498; SU 1498; SU1498; Tyrphostin SU 1498
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PathwayOthers
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TargetOther Targets
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RecptorVEGFR2
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Research Area——
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Indication——
Chemical Information
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CAS Number168835-82-3
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Formula Weight390.53
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Molecular FormulaC25H30N2O2
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Purity98%
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SolubilityDMSO : ≥ 150 mg/mL. 384.10 mM
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SMILESO=C(/C(=C/c1cc(C(C)C)c(O)c(C(C)C)c1)/C#N)NCCCc1ccccc1
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Chemical Name(2E)-2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-2-propenamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1: Gawlak G, et al.Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1062-70.
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